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Close-up of two slices of juicy meatloaf with a glossy ketchup glaze, served over creamy mashed potatoes.

Venison Meatloaf: The Ultimate Guide to a Flavorful and Healthy Meal


  • Author: Hayat Amertous
  • Total Time: 1 hour 10 minutes
  • Yield: 1 loaf (about 1.52 lbs) 1x
  • Diet: Low Calorie

Description

This Juicy Venison Meatloaf is a lean, protein-packed twist on the classic comfort food. With its bold, slightly gamey flavor, venison pairs perfectly with rich seasonings and moisture-locking ingredients to create a tender, mouthwatering meatloaf. Whether you’re a hunter looking to make use of wild game or simply seeking a healthier red meat alternative, this recipe delivers incredible taste and texture. Serve it with mashed potatoes and a savory glaze for the ultimate hearty meal.


Ingredients

Scale

Meat & Fat Blend:

  • 1 ½ lbs ground venison
  • ½ lb ground pork or ground beef (for added fat & moisture)

Binding & Moisture Ingredients:

  • 1 large egg
  • ½ cup breadcrumbs (or crushed crackers/oats for gluten-free)
  • ½ cup whole milk (or heavy cream for extra moisture)
  • 1 small onion, finely diced
  • 2 cloves garlic, minced
  • ½ cup mushrooms, finely chopped (optional, for extra umami)
  • ¼ cup shredded carrot or zucchini (optional, adds moisture)

Seasonings & Spices:

  • 1 tbsp Worcestershire sauce
  • 2 tbsp ketchup (or tomato paste for a richer taste)
  • 1 tsp Dijon mustard
  • 1 tsp salt
  • ½ tsp black pepper
  • 1 tsp garlic powder
  • 1 tsp onion powder
  • ½ tsp smoked paprika
  • ½ tsp dried thyme
  • ½ tsp dried oregano

Glaze:

 

  • ½ cup ketchup
  • 2 tbsp brown sugar
  • 1 tbsp Worcestershire sauce
  • 1 tsp Dijon mustard

Instructions

  • Preheat Oven – Set your oven to 350°F (175°C). Lightly grease a loaf pan or line it with parchment paper.

  • Prepare the Mixture – In a large mixing bowl, combine ground venison and ground pork/beef. Add the diced onion, garlic, mushrooms, and shredded carrot or zucchini.

  • Add Binders & Moisture – Beat the egg in a small bowl, then add it to the meat mixture along with breadcrumbs and milk. Mix gently to combine.

  • Seasoning & Flavor Boosters – Add Worcestershire sauce, ketchup, Dijon mustard, salt, black pepper, garlic powder, onion powder, smoked paprika, thyme, and oregano. Mix until just combined—avoid overmixing to keep the meatloaf tender.

  • Shape the Meatloaf – Transfer the mixture to the prepared loaf pan. Press it lightly into shape, but don’t pack it too tightly to prevent a dense texture.

  • Prepare the Glaze – In a small bowl, mix ketchup, brown sugar, Worcestershire sauce, and Dijon mustard. Spread half the glaze evenly over the top of the meatloaf.

  • Bake the Meatloaf – Place the meatloaf in the oven and bake for 45–55 minutes, or until the internal temperature reaches 145–150°F (for medium).

  • Add the Final Glaze – About 10 minutes before the meatloaf is done, spread the remaining glaze on top and return it to the oven.

  • Rest & Serve – Remove the meatloaf from the oven and let it rest for 10–15 minutes before slicing. This allows the juices to redistribute, keeping it moist and flavorful.

 

  • Enjoy! Serve warm with your favorite sides, such as garlic mashed potatoes, roasted vegetables, or a tangy cranberry compote.

Notes

  • Mix Meat for Moisture – Since venison is lean, adding pork fat, ground pork, or beef prevents dryness. A ratio of 80% venison to 20% fat is ideal.
  • Don’t Overmix – Overworking the mixture can make the meatloaf dense and tough. Mix gently until just combined.
  • Use a Meat Thermometer – Venison meatloaf is best at 145–150°F. Overcooking will make it dry.
  • Customize the Glaze – Add a smoky BBQ sauce or a tangy balsamic glaze for a unique twist.

 

  • Make It Keto-Friendly – Swap breadcrumbs for crushed pork rinds or almond flour and use unsweetened tomato paste in the glaze.
  • Prep Time: 15 minutes
  • Cook Time: 45–55 minutes
  • Category: American, Wild Game
  • Method: Baking
  • Cuisine: Main Course

Nutrition

  • Serving Size: 6 servings
  • Calories: 290
  • Sugar: 4g (from ketchup glaze)
  • Sodium: ~450mg (varies with seasoning)
  • Fat: 12g
  • Saturated Fat: 4g
  • Unsaturated Fat: 6g
  • Trans Fat: 0g
  • Carbohydrates: 10g
  • Fiber: 1g
  • Protein: 30g
  • Cholesterol: ~85mg

Keywords: Venison meatloaf, wild game meatloaf, healthy meatloaf, low-fat meatloaf, protein-rich dinner, keto meatloaf, lean meatloaf, easy meatloaf recipe, comfort food, hunting recipes